Table 3 The 20 most down-regulated in mouse macrophage cell line RAW 264.7 infected with each B. abortus compare to uninfected macrophage
Gene symbol | Description | 1119-3 | C10 | C29 | D6 | D7 | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | FC | P-value | FC | P-value | FC | P-value | FC | P-value | FC | P-value |
Cytip | Cytohesin 1 interacting protein | −2.9 | 1.62E-11 | −2.16 | 1.08E-06 | −2.35 | 1.19E-08 | −2.82 | 6.46E-12 | −2.53 | 3.53E-13 |
Cxcr4 | Chemokine (C-X-C motif) receptor 4 | −2.17 | 6.43E-06 | −1.81 | 8.36E-04 | −2.13 | 9.94E-07 | −2.63 | 2.59E-10 | −2.12 | 4.46E-07 |
Klhl6 | Kelch-like 6 (Drosophila) | −2.1 | 5.71E-07 | −1.73 | 3.39E-04 | −1.73 | 8.32E-05 | −2.15 | 2.06E-06 | −1.91 | 1.06E-06 |
Enc1 | Ectodermal-neural cortex 1 | −2.01 | 1.01E-04 | −1.77 | 1.71E-03 | −1.9 | 1.03E-04 | −1.98 | 5.11E-05 | −1.98 | 9.61E-07 |
Slc40a1 | Solute carrier family 40 (iron-regulated transporter), member 1 | −1.95 | 5.21E-06 | −1.83 | 2.61E-05 | −1.8 | 1.17E-05 | −2.31 | 1.15E-07 | −1.92 | 6.60E-07 |
Tmem86a | Transmembrane protein 86A | −1.85 | 1.23E-03 | −1.51 | >0.05 | −1.79 | 7.58E-04 | −2.02 | 2.43E-05 | −1.79 | 4.44E-04 |
BC039093 | cDNA sequence BC039093 | −1.84 | 9.07E-04 | −1.54 | >0.05 | −1.7 | 2.06E-03 | −1.92 | 1.33E-04 | −1.73 | 1.73E-04 |
5430435G22Rik | RIKEN cDNA 5430435G22 gene | −1.81 | 2.26E-03 | −1.57 | 0.04 | −1.74 | 1.90E-03 | −1.93 | 1.25E-04 | −1.68 | 5.34E-04 |
Tmem51 | Transmembrane protein 51 | −1.81 | 3.69E-04 | −1.57 | 0.01 | −1.65 | 8.54E-04 | −2.08 | 9.03E-06 | −1.86 | 4.84E-06 |
Lhfpl2 | Lipoma HMGIC fusion partner-like 2 | −1.78 | 1.60E-04 | −1.52 | 0.02 | −1.8 | 8.18E-06 | −1.96 | 6.97E-05 | −1.82 | 6.49E-06 |
Slc37a1 | 10 days neonate skin cDNA, RIKEN full-length enriched library, clone:4732478E01 product:solute carrier family 37 (glycerol-3-phosphate transporter), member 1, full insert sequence | −1.78 | 3.92E-03 | −1.57 | 0.04 | −1.61 | 0.02 | −1.8 | 1.16E-03 | −1.73 | 2.98E-04 |
C130050O18Rik | RIKEN cDNA C130050O18 gene | −1.78 | 3.88E-03 | −1.62 | 0.02 | −1.85 | 2.48E-04 | −1.94 | 1.12E-04 | −1.81 | 1.05E-04 |
AI595366 | Leucine rich repeat containing 14B | −1.77 | 3.95E-03 | −1.51 | >0.05 | −1.59 | 0.02 | −1.85 | 4.90E-04 | −1.63 | 0.01 |
B930041F14Rik | RIKEN cDNA B930041F14 gene | −1.75 | 4.00E-03 | −1.54 | >0.05 | −1.67 | 3.77E-03 | −1.87 | 3.39E-04 | −1.74 | 1.36E-04 |
LOC100045981 | Similar to synaptotagmin XI | −1.74 | 5.45E-03 | −1.58 | 0.04 | −1.65 | 6.70E-03 | −1.97 | 5.60E-05 | −1.85 | 1.29E-05 |
Arrdc3 | Arrestin domain containing 3 | −1.74 | 6.50E-03 | −1.6 | 0.03 | −1.71 | 2.72E-03 | −1.95 | 9.29E-05 | −1.55 | 0.02 |
Tspan14 | Tetraspanin 14 | −1.73 | 1.60E-03 | −1.43 | >0.05 | −1.45 | 0.04 | −1.72 | 4.53E-03 | −1.52 | 0.01 |
Lzts2 | Leucine zipper, putative tumor suppressor 2 | −1.72 | 8.22E-03 | −1.63 | 0.02 | −1.74 | 1.82E-03 | −1.87 | 3.22E-04 | −1.76 | 9.06E-04 |
Fblim1 | Filamin binding LIM protein 1 | −1.72 | 2.29E-03 | −1.53 | 0.04 | −1.49 | 0.02 | −1.61 | 0.02 | −1.56 | 5.47E-03 |
Phf17 | PHD finger protein 17 | −1.7 | 0.01 | −1.59 | 0.03 | −1.62 | 0.01 | −1.72 | 4.73E-03 | −1.55 | 8.58E-03 |