Table 1 Error of the RAS values of single DNA pools

all SNPs (N = 772731)

0.25 (0.138)

0.141 (0.081)

0.257 (0.144)

0.146 (0.083)

0.267 (0.127)

0.14 (0.09)

NA

NA

10000 SNPs MAF >1%

0.202 (0.108)

0.112 (0.066)

0.209 (0.114)

0.117 (0.068)

0.185 (0.1)

0.103 (0.06)

0.0642 (0.026)

0.031 (0.024)

10000 SNPs MAF >5%

0.192 (0.0981)

0.104 (0.064)

0.199 (0.104)

0.108 (0.065)

0.170 (0.0902)

0.0938 (0.057)

NA

NA

Pool 1

RAS (tan-corrected n = 0.5)

RAS (tan-corrected n = 1)

RAS (tan-corrected n = 2)

SNP set

Q90 (Median)

Mean (SD)

Q90 (Median)

Mean (SD)

Q90 (Median)

Mean (SD)

all SNPs (N = 772731)

0.122 (0.0417)

0.0577 (0.11)

0.13 (0.0438)

0.0628 (0.15)

0.16 (0.0539)

0.11 (1.6)

10000 SNPs MAF >1%

0.0744 (0.0306)

0.0362 (0.028)

0.0806 (0.0333)

0.0392 (0.03)

0.104 (0.0464)

0.0523 (0.037)

10000 SNPs MAF >5%

0.0724 (0.0298)

0.0353 (0.027)

0.0783 (0.0325)

0.0382 (0.029)

0.101 (0.046)

0.0515 (0.036)

Pool 2

RAS (Birdseed2)

RAS (CEL)

RAS (k-corrected)

RAS (PPC-corrected)

SNP set

Q90 (Median)

Mean (SD)

Q90 (Median)

Mean (SD)

Q90 (Median)

Mean (SD)

Q90 (Median)

Mean (SD)

all SNPs (N = 772731)

0.252 (0.139)

0.142 (0.082)

0.262 (0.147)

0.149 (0.085)

0.267 (0.128)

0.14 (0.09)

NA

NA

10000 SNPs MAF >1%

0.199 (0.107)

0.110 (0.066)

0.206 (0.112)

0.114 (0.068)

0.18 (0.0993)

0.101 (0.059)

0.0641 (0.0251)

0.0306 (0.024)

10000 SNPs MAF >5%

0.191 (0.0976)

0.103 (0.064)

0.195 (0.101)

0.105 (0.065)

0.165 (0.0893)

0.0914 (0.055)

NA

NA

Pool 2

RAS (tan-corrected n = 0.5)

RAS (tan-corrected n = 1)

RAS (tan-corrected n = 2)

SNP set

Q90 (Median)

Mean (SD)

Q90 (Median)

Mean (SD)

Q90 (Median)

Mean (SD)

all SNPs (N = 772731)

0.123 (0.043)

0.058 (0.061)

0.129 (0.0451)

0.0625 (0.14)

0.157 (0.0548)

0.107 (2.6)

10000 SNPs MAF >1%

0.075 (0.0304)

0.0363 (0.028)

0.0804 (0.0329)

0.0388 (0.03)

0.101 (0.0442)

0.0506 (0.037)

10000 SNPs MAF >5%

0.0737 (0.0304)

0.0359 (0.027)

0.0786 (0.0326)

0.0383 (0.029)

0.0993 (0.0442)

0.0499 (0.035)