Figure 3

Cartoon of the primary transcript encoding the EBNA proteins. Exons are indicated with black or grey rectangles and the genomic location of the end of each protein-coding region is indicated above. The identical W1 and W2 coding exons that compose most of EBNA-LP are shown in grey. The Cp and upstream Wp promoter sites are indicated by bent arrows with the genome coordinates of the transcription start sites given above. The boxed region zooms in to show the 5′ end of the pre-mRNA, including the locations of the predicted long hairpin (HP) and ebv-sisRNA-1, colored yellow and green, respectively, with their genome coordinates given in parentheses. RNAz-predicted structured regions are shown in blue and labeled L17 to L23 for loci 17 to 23 (genome coordinates for these loci are in Additional file 1).