Figure 1
From: Genome-wide modeling of complex phenotypes in Caenorhabditis elegans and Drosophila melanogaster
Network Diagram of the single C. elegans gene set “life_span_variant” as produced by Ingenuity Pathway Analysis (IPA) shows members of the geneset (shaded) as well as regulatory or transcriptional partners not found (unshaded) in the original geneset. The network highlights the central role of insulin, ERK family members, and PI3 Kinase as important contributors to longevity in worms.