Table 4 Enriched GO biological processes for differentially expressed genes
From: Comparative toxicogenomic responses of mercuric and methyl-mercury
Mercurial | Toxicity | Change in expression | Biological process (p-value) |
|---|---|---|---|
MeHgCl | Sub-toxic | up-regulated | Metabolic process (0.00097) |
Low-toxic | up-regulated | Lipid glycosylation (4.6E-05) | |
Response to heat (0.00084) | |||
Carbohydrate metabolic process (0.0084) | |||
| Â | Oxidation reduction (0.04) | ||
| Â | down-regulated | Regulation of transcription (0.032) | |
High-toxic | up-regulated | Post-translational protein modification (3.4E-67) | |
Vitelline membrane formation (8.5E-07) | |||
Lipid glycosylation (1.1E-05) | |||
Response to heat (0.0022) | |||
| Â | Enterobactin biosynthetic process (0.044) | ||
down-regulated | Cell adhesion (9.5E-06) | ||
Body morphogenesis (1.8E-05) | |||
Cell-matrix adhesion (4.7E-05) | |||
Chitin catabolic process (0.00021) | |||
Regulation of transcription (0.0012) | |||
Cell wall macromolecule catabolic process (0.025) | |||
Defense response (0.0035) | |||
Tail morphogenesis (0.0044) | |||
Proteolysis (0.0046) | |||
Cilium morphogenesis (0.012) | |||
Neuron recognition (0.021) | |||
Lipid transport (0.021) | |||
Ubiquitin-dependent catabolic process (0.032) | |||
Response to oxidative stress (0.035) | |||
Protein-DNA complex assembly (0.042) | |||
| Â | Regulation of cell migration (0.046) | ||
HgCl2 | Low-toxic | up-regulated | Proteolysis (7.4E-06) |
High-toxic | up-regulated | Lipid glycosylation (2.5E-14) | |
Transmembrane transport (1.1E-06) | |||
Carbohydrate metabolic process (2.1E-06) | |||
Extracellular matrix organization (1.3E-05) | |||
| Â | Oxidation reduction (0.0084) | ||
| Â | down-regulated | Body morphogenesis (6.8E-10) | |
Locomotion (0.018) | |||
Morphogenesis of an epithelium (0.024) | |||
| Â | Â | Regulation of multicellular organism growth (0.036) |