Figure 3
From: Genome-scale cold stress response regulatory networks in ten Arabidopsis thalianaecotypes
Transcriptional regulatory network constructed using cold stress microarray data from 10 A. thaliana ecotypes. (A) Topological overview of the constructed network. The network contains 1,275 genes (nodes) and 7,720 connections. Transcription factors are marked as green triangles and target genes are marked as red circles. Predicted regulatory interactions are shown as arrow (→) for activation (6,731) and down-horizontal bar (┤) as repression (989). Network was visualized in Cytoscape software using ‘Force-Directed Layout’. (B) Scale-free behaviour of the predicted network. This plot shows the power-law degree distribution of the network P (k) at correlation thresholds (r ≥ 0.8). Here k indicates connectivity, and P (k) indicates the connectivity distribution of the genes (nodes) in the network. This satisfies the existing notion about scale free behaviour of biological networks. Few TFs in the network are highly connected (hubs) than others.