Figure 2
Conserved differential gene expression in response to ethanol with implicit model differences in direction of change. A: Venn diagram highlights common set of 29 differentially expressed genes in prefrontal cortex of human alcoholics (as reported by [14]) and ethanol-treated mice (current results); B: Directionality of expression changes in common set of 29 differentially expressed genes referred to in A; C: Venn diagram highlights common set of 84 differentially expressed genes in prefrontal cortex of human alcoholics (as reported by [15]) and ethanol-treated mice (current study); D: Directionality of expression change in common set of 84 differentially expressed genes referred to in C. P values empirically assessed after 105 and 107 Monte Carlo simulations, respectively.