Figure 1

Spatial organisation of the BAp chromosome compared with that of E. coli . First line bars: genes involved in aerobic/anaerobic metabolism (dark blue), DNA replication (orange), rrn genes (upper red), and transition phase (brown). Second line bars: selected genes involved in the control of DNA topology (green). Third line bars: selected genes encoding NAPs (light blue). Fourth line bars: selected genes involved in modulating RNAP activity, including σ factor-utilization regulators (light green), secondary channel-binding proteins (pink), termination/elongation factors (red), and RNAP subunits (black). Grey dotted lines link pairs of orthologous genes between BAp and E. coli. Selected genes are those described by Sobetzko et al. [39].