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Figure 2 | BMC Genomics

Figure 2

From: Forfeited hepatogenesis program and increased embryonic stem cell traits in young hepatocellular carcinoma (HCC) comparing to elderly HCC

Figure 2

Interaction network and gene set enrichment analyses as frameworks for interpreting yHCC biology. (A) A genetic network composed of multiple yHCC genes. This network is displayed graphically as nodes (gene products) and edges (biological relationships between nodes) mapped by the Ingenuity Pathway Analysis (IPA) tool. The intensity of the node color indicates the degree of upregulation. (B) Canonical pathway analysis. Genes that are more abundant in yHCC were subjected to IPA search. (C) Altered biological modules in yHCCs. 282 probe sets that are more abundant in yHCC were subjected to Gene Ontology database search. The number of genes, gene symbols, and p values for each category that are significantly enriched are listed (p < 0.05).

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BMC Genomics

ISSN: 1471-2164

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