Table 5 IPA results
From: STaRRRT: a table of short tandem repeats in regulatory regions of the human genome
Top Bio Functions | Molecules (n) | p-value |
|---|---|---|
Diseases and disorders | ||
Neurological disease | 443 | 1.27E-04 - 4.94E-02 |
Psychological disorders | 236 | 1.81E-04 - 4.94E-02 |
Developmental disorder | 132 | 9.19E-04 - 4.24E-02 |
Antimicrobial response | 29 | 1.38E-03 - 2.00E-02 |
Infectious disease | 418 | 2.25E-03 - 4.17E-02 |
Molecular and cellular functions | ||
Cellular movement | 325 | 3.39E-04 - 4.81E-02 |
Cell death and survival | 501 | 6.18E-04 - 4.83E-02 |
Cell-to-cell signaling and interaction | 119 | 1.07E-03 - 4.81E-02 |
Cellular development | 290 | 1.17E-03 - 4.37E-02 |
Cellular growth and proliferation | 192 | 1.47E-03 - 4.81E-02 |
Physiological system development and functions | ||
Cardiovascular system development and function | 167 | 7.56E-06 - 4.70E-02 |
Organismal development | 146 | 3.20E-05 - 4.37E-02 |
Humoral immune response | 12 | 1.38E-03 - 4.81E-02 |
Reproductive system development and function | 31 | 1.47E-03 - 4.17E-02 |
Hematological system development and function | 107 | 1.74E-03 - 4.81E-02 |
Top 20 canonical pathways | Ratio | p-value |
NGF signaling | 34/111 (0.306) | 3.16E-03 |
Pyridoxal 5'-phosphate salvage pathway | 22/62 (0.355) | 4.22E-03 |
Reelin signaling in neurons | 26/82 (0.317) | 6.29E-03 |
Neuropathic pain signaling in dorsal horn neurons | 31/102 (0.304) | 6.92E-03 |
GNRH signaling | 38/135 (0.281) | 7.00E-03 |
Cellular effects of sildenafil (Viagra) | 37/127 (0.291) | 9.28E-03 |
Calcium signaling | 48/189 (0.254) | 1.01E-02 |
Factors promoting cardiogenesis in vertebrates | 27/91 (0.297) | 1.27E-02 |
Synaptic long-term depression | 39/142 (0.275) | 1.51E-02 |
B cell receptor signaling | 43/162 (0.265) | 1.95E-02 |
FGF signaling | 26/88 (0.295) | 2.01E-02 |
mTOR signaling | 49/189 (0.259) | 2.06E-02 |
Gɑq signaling | 40/157 (0.255) | 2.33E-02 |
Dopamine-DARPP32 feedback in cAMP signaling | 43/161 (0.267) | 2.40E-02 |
D-myo-inositol (1,4,5)-triphosphate biosynthesis | 10/26 (0.385) | 2.66E-02 |
PPARɑ/RXRɑ activation | 44/173 (0.254) | 2.86E-02 |
NF-κB activation by viruses | 22/79 (0.278) | 3.18E-02 |
Xenobiotic metabolism signaling | 66/268 (0.246) | 3.20E-02 |
Antioxidant action of vitamin C | 27/98 (0.276) | 3.43E-02 |
Maturity onset diabetes of young (MODY) signaling | 8/22 (0.364) | 3.64E-02 |