Figure 1
From: A new computational approach redefines the subtelomeric vir superfamily of Plasmodium vivax
Pipeline procedure to reclassify vir genes. The procedure starts with the 345 VIR proteins annotated at PlasmoDB 7.2. Two graph pre-processing strategies [14, 16] and the Markov Clustering Algorithm [15] are run to obtain sequence clusters. Then, the Homology Block concept [17] is used to further validate the clustering approach based on comparisons of conserved motifs. Graph figures were obtained using BioLayout [18].