Iterative feature removal yields highly discriminative pathways

BMC Genomics

Table 5 T-test ranking of genes in the BCell+CAM classifier

Gene	IGHM	IGHD	IGHV3-23	CD200	CD24	CD9	CD22	CD38	CD19
Rank	831	1238	5659	122	348	4620	391	337	508
Gene	CD79A	CD86	CD40	CD72		ICAM4	ICAM3	ICAM5	MADCAM1
Rank	402	2198	2406	1048		2462	564	4250	8481

The BCell+CAM classifier is 100% accurate on the test data, while consisting of genes that are relatively low ranking in terms of univariate separability. The table shows gene names and the t-test rankings within the total of 12,023 genes (bold values for those within the first 500). A blank cell separates the 13 BCell genes from the 4 CAM genes.

ISSN: 1471-2164