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Figure 1 | BMC Genomics

Figure 1

From: RETRACTED ARTICLE: Gene expression analysis indicates CB1 receptor upregulation in the hippocampus and neurotoxic effects in the frontal cortex 3 weeks after single-dose MDMA administration in Dark Agouti rats

Figure 1

Venn-diagram representation of significantly altered mRNAs. Venn-diagrams showing the number of significantly (minimum probability of positive log ratio (MinPplr) < 0.001) up- or downregulated genes in the hippocampus (HC), frontal cortex (FC) and dorsal Raphe (DR) of Dark Agouti (DA) rats 3 weeks after a single-dose of 3,4-methylenedioxymethamphetamine (MDMA) (15 mg/kg, intraperitoneally). Altogether 615 genes’ showed altered expression, 481, 155, 14 genes in the HC, FC, DR regions, respectively. Among them only 1 genes’ expression altered significantly in all three regions and 36 genes differed significantly compared to saline controls in both the FC and HC groups. See text for further details.

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BMC Genomics

ISSN: 1471-2164

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