Figure 6From: A protein domain-centric approach for the comparative analysis of human and yeast phenotypically relevant mutationsIncrease of domain hotspots by incorporating yeast mutational data. The number of position-based (A) and feature-based (B) domain hotspots at the 1.6, 1.3, and 1.0 threshold. This figure visually represents the number of domain hotspots formed from human mutations (blue), the number of domain hotspots from yeast mutations (orange), and the number of new multi-species domain hotspots that did not reach significance in either the yeast or human analyses individually (purple).Back to article page