Skip to main content
Figure 3 | BMC Genomics

Figure 3

From: Assessment of computational methods for predicting the effects of missense mutations in human cancers

Figure 3

SIFT predicts high frequency cancer mutations and low frequency SNPs to be more deleterious. (A, B) The frequency of mutations in COSMIC correlates with the likelihood to be deleterious according to SIFT score (mutations that are predicted to be deleterious have low SIFT scores). (C, D) The minor allele frequency of dbSNP polymorphisms correlates with the likelihood to be benign according to SIFT score.

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us