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Figure 4 | BMC Genomics

Figure 4

From: Multiscale modeling of the causal functional roles of nsSNPs in a genome-wide association study: application to hypoxia

Figure 4

The model structure of HDAC4. The yellow spheres represent mutated amino acid A1075. Green sticks represent residues co-evolved with A1075. Red circle represents zinc binding sites of HDAC4. This model structure is built using Modeller [65] based on the sequence alignment between HDAC4 and PDB structure 2VQW. The sequence identity between HDAC4 (819-1223) and 2VQW is 58%.

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BMC Genomics

ISSN: 1471-2164

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