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Table 2 ATC second sublevel categories significantly enriched in illicit drugs compared to other drugsa

From: Exploring drug-target interaction networks of illicit drugs

ATC code

ATC therapeutic subgroup

# of illicit drugs (%b)

# of other drugs (%c)

p-valued

N05

Psycholeptics

24 (48.0)

3 (0.5)

1.2 × 10-26

N01

Anesthetics

5 (10.0)

0 (0)

2.3 × 10-6

A08

Antiobesity preparations, excluding diet products

4 (8.0)

1 (0.2)

1.5 × 10-4

N02

Analgesics

6 (12.0)

11 (1.9)

1.0 × 10-3

A14

Anabolic agents for systemic use

2 (4.0)

0 (0)

5.9 × 10-3

N06

Psychoanaleptics

3 (6.0)

4 (0.7)

0.012

R05

Cough and cold preparations

2 (4.0)

1 (0.2)

0.017

  1. aThe other drugs represent the drugs in the full drug-target network excluding illicit drugs and illicit-related drugs. Among those other drugs, 594 have ATC second sublevel classifications.
  2. bThe proportion of illicit drugs belong to a given ATC category among the 50 illicit drugs with ATC second sublevel classifications.
  3. cThe proportion of other drugs belong to a given ATC category among the 594 other drugs with ATC second sublevel classifications.
  4. dp-value was calculated by Fisher's exact test.