Table 3 ATC second sublevel categories significantly enriched in illicit-related drugs compared to other drugsa
From: Exploring drug-target interaction networks of illicit drugs
ATC code | ATC therapeutic subgroup | # of illicit-related drugs (%b) | # of other drugs (%c) | p-value |
|---|---|---|---|---|
N05 | Psycholeptics | 54 (14.8) | 3 (0.5) | 1.4 × 10-20 |
N06 | Psychoanaleptics | 38 (10.4) | 4 (0.7) | 6.7 × 10-13 |
N01 | Anesthetics | 25 (6.9) | 0 (0) | 1.9 × 10-11 |
D07 | Corticosteroids, dermatological preparations | 23 (6.3) | 0 (0) | 1.4 × 10-10 |
N04 | Anti-Parkinson drugs | 17 (4.7) | 2 (0.3) | 4.2 × 10-6 |
G03 | Sex hormones and modulators of the genital system | 21 (5.8) | 5 (0.8) | 1.1 × 10-5 |
H02 | Corticosteroids for systemic use | 12 (3.3) | 1 (0.2) | 7.0 × 10-5 |
N07 | Other nervous system drugs | 14 (3.8) | 5 (0.8) | 2.9 × 10-3 |
A03 | Drugs for functional gastrointestinal disorders | 14 (3.8) | 5 (0.8) | 2.9 × 10-3 |
C05 | Vasoprotectives | 12 (3.3) | 4 (0.7) | 3.2 × 10-3 |
R01 | Nasal preparations | 16 (4.4) | 7 (1.2) | 3.6 × 10-3 |
S01 | Ophthalmologicals | 43 (11.8) | 44 (7.4) | 0.027 |