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Figure 2 | BMC Genomics

Figure 2

From: Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates

Figure 2

Multidimensional scaling representation for Calu-3 MERS-CoV and SARS-CoV infections. Calu-3 2B4 cells were infected with either MERS-CoV SA 1 or MERS-CoV Eng 1 (MOI 5) and cell lysates were harvested at 0, 3, 7, 12, 18 and 24 hpi. Calu-3 2B4 cells were infected with icSARS-CoV (MOI 5) and cell lysates were harvested at 0, 3, 7, 12, 24, 30 and 36 hpi. Samples are clustered based on 6432 DE genes changing in at least one virus condition and at one time-point The quality of the representation is provided by the Kruskal Stress criteria, with the relatively low percentage of Kruskal stress (8.22%) suggesting a faithful 2D representation of the statistically observed transcriptional differences between MERS-CoV SA 1, MERS-CoV Eng 1 and icSARS-CoV.

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BMC Genomics

ISSN: 1471-2164

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