Table 2 Illustrating examples of using MTBs to functionally annotate miRNAs
Enriched GO term | |||
|---|---|---|---|
MTB ID | Total number of mRNAs | mRNAs annotated with the GO term | miRNAs |
GO:0004674 Protein serine/threonine kinase activity | |||
1 | 4 | AAK1, MAPK1, PDK3 | miR-17, miR-20b, miR-93, miR-320a |
GO:0000792 Heterochromatin | |||
2 | 4 | CBX5, HMGA2, RNF20 | let-7b, let-7c, let-7d, let-7e, let-7g, miR-185 |
GO:0007219 Notch signaling pathway | |||
3 | 3 | CDK6, TNRC6B | miR-15a, miR-34a, miR-449a, miR-497 |
GO:0043161 Proteasome-mediated ubiquitin-dependent | |||
protein catabolic process | |||
4 | 19 | EDEM1, UBE2W, WWP2 | miR-25, miR-32, miR-363 |