Figure 1
From: Identification of a novel Parkinson’s disease locus via stratified genome-wide association study
Genome-wide association P values for All-PD (A), Sporadic-PD (B) and Familial-PD (C). The Manhattan plots (A.1, B.1, C.1) show the -Log10 P values for association of SNPs with PD within each stratification, plotted according to their location across each chromosome. The horizontal red line is P = 5×10-8. The quantile-quantile (QQ) plots (A.2, B.2, C.2) depict the distribution of expected P-values for no disease association (black line) vs. the observed P-values for all SNPs genome-wide (red line), and excluding SNCA (Chr 4 - bp: 90453000 to 91867000), HLA (Chr 6 - bp: 30615000 to 32963000) and MAPT (Chr 17 - bp: 42285000 to 44866000) (blue line).