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Table 3 A summary of GO terms that are significantly enriched in 1st (early) or 2nd (late) age-positions in VL muscles or brain cortex

From: Major aging-associated RNA expressions change at two distinct age-positions

 

1st age-position

2nd age-position

VL muscles

Muscle contraction;

Contractile fiber;

Calcium transport;

Mitochondria;

Lipid metabolism

Apoptosis;

 

Estrogen receptor signaling;

 

Chromatin silencing;

 

Phagocytic vesicle;

 

RNA processing

Brain cortex

Nervous system;

Nerve cell system;

Calcium transport;

Apoptosis;

Lipid metabolism;

Mitochondria;

Actin cytoskeleton;

Nucleotide biosynthesis;

Interphase;

Microtubule cytoskeleton;

Apoptosis;

Cell migration;

Cell migration;

Ion homeostasis;

Nucleotide biosynthesis;

Insulin-like growth factor signaling;

Energy biogenesis;

Hormone secretion

Androgen signaling;

 

Protein tyrosine kinase;

 

Endocytic vesicle

 
  1. A list of significantly enriched GO terms in the early and late age-positions for VL muscles and brain cortex datasets. GO terms are ordered according to their significant enrichment. In bold are similar GO terms in both tissues. A complete list of the GO terms hierarchical trees can be found in Additional file 3: Tables S8–11.