Table 1 Pathway classes recurrently and significantly altered in aneuploid cell lines
From: Unique features of the transcriptional response to model aneuploidy in human cells
Replication | Transcription | Ribosome | Golgi | ER | Lysosomes | Membrane metabolism | Vacuole | Mitochondria | Spliceosome | MHC class proteins | |
|---|---|---|---|---|---|---|---|---|---|---|---|
HCT116 5/4 | - | - | - | + | + | + | + | + | - | - | + |
HCT116 3/3 | - | - | - | + | + | + | + | + | - | - | |
HCT116 5/4* | - | - | - | + | + | + | (+) | + | - | / | + |
HPT1 | - | - | + | - | + | + | + | + | / | - | + |
HPT2 | - | - | - | + | + | + | + | + | + | - | + |
RPE1 12/3 5/3 | - | - | + | + | + | + | + | + | + | + | + |
RPE1 21/3* | - | - | - | + | + | + | + | + | - | - | + |
DLD1 3/3 | - | - | - | + | / | / | + | + | - | - | / |
DLD1 7/3 | - | - | / | / | / | / | / | + | / | - | / |
DLD1 13/3 | - | - | - | + | / | / | + | + | - | - | / |
HE35 8/3_1 | +/- | - | - | - | - / | / | +/- | / | + | + | / |
HE35 8/3_2 | - | - | - | + | + | / | +/- | / | +/- | + | + |
HE35 8/3_3 | - | -/+ | - | + | + | + | +/- | + | (+) | + | / |