Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type

Table 1 Number of meQTLs detected in each dataset and the number and percent overlapping between datasets, in the form number (percent)

	# of	PB	CB A	CB B	FCTX	TCTX	CRBLM	PONS
Cohort	meQTLs	724	629	2055	2853	3029	2802	2150
PB	724	-	319 (50.7)	366 (17.8)	254 (8.9)	234 (7.7)	185 (6.6)	203 (9.4)
CB A	629	319 (44.1)	-	437 (21.3)	205 (7.2)	196 (6.5)	165 (5.9)	211 (9.8)
CB B	2055	366 (50.6)	437 (69.5)	-	650 (22.8)	649 (21.4)	517 (18.5)	587 (27.3)
FCTX	2853	254 (35.1)	205 (32.6)	650 (31.6)	-	2046 (67.6)	1078 (38.5)	1414 (65.8)
TCTX	3029	234 (33.3)	196 (31.2)	649 (31.6)	2046 (71.7)	-	1091 (38.9)	1480 (68.9)
CRBLM	2802	185 (25.6)	165 (26.2)	517 (25.2)	1078 (37.8)	1091 (36.0)	-	1004 (46.7)
PONS	2150	203 (28.0)	211 (33.6)	587 (28.6)	1414 (49.6)	1480 (48.9)	1004 (35.8)	-

Bold numbers are the total meQTLs identified in each cohort and serve as the denominator for calculation of percentages.
Upper triangle: number (percent) of meQTLs identified in top dataset (column header) that were also identified in left-hand dataset (row header).
Lower triangle: number (percent) of meQTLs identified in left-hand dataset (row header) that were also identified in top dataset (column header).
Abbreviations: CB B cord blood B, TCTX temporal cortex, FCTX frontal cortex, PONS pons, CRBLM cerebellum, CB A cord blood A, and PB peripheral blood.

ISSN: 1471-2164