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Table 5 Detailed information on the nearest and most significant SNPs from previous GWAS to the 31 differentially expressed genes between the mammary gland of two cows with high milk protein and fat percentage and two cows with low protein and fat percentage

From: Transcriptional profiling of mammary gland in Holstein cows with extremely different milk protein and fat percentage using RNA sequencing

Gene name

Gene position (bp)1

Nearest and most significant SNPs of GWAS

Traits

Raw pvalue

Reference

 

Distance

Name

Position (bp)2

   

SAA3

Chr29: 26668046–26671801

49.5 Kb

ARS-BFGL-NGS-24998

26721324

PP

2.96E-08

Cole et al., BMC Genomics, 2011 [8]

  

4.2 Mb

UA-IFASA-8605

30901735

FP, PP

4.90E-13, 1.50E-16

 

HEATR7B2

Chr20: 33455667–33528569

23.2 Kb

ARS-BFGL-BAC-2469

33433160

PP

1.21E-08

Jiang et al., Plos One, 2010 [6]

  

2.6 Mb

rs41640170

36097136

PP

1E-6.88

Schopen et al., J Dairy Sci, 2011 [9]

TRIB3

Chr13: 61176217–61187210

2.1 Mb

BFGL-NGS-119420

59101909

FP, PP

1.14E-21, 3.49E-18

Cole et al., BMC Genomics, 2011 [8]

  

9.3 Mb

rs29021058

70524323

PP

0.0018

Kolbehdari et al., J Anim Breed Genet, 2009 [5]

SESN2

Chr2: 125698159–125714128

2.0 Mb

ARS-BFGL-NGS-69013

123717269

FP, PP

1.46E-11, 3.26E-09

Cole et al., BMC Genomics, 2011 [8]

  

2.7 Mb

BTA-31250-no-rs

128437731

FP, PP

3.75E-10, 1.26E-24

 

CHAC1

Chr10: 36598393–36600764

0.16 Mb

Hapmap53714-rs29017586

36758715

FP, PP

9.84E-07, 6.64E-12

Cole et al., BMC Genomics, 2011 [8]

NR4A1

Chr5: 27977006–27992869

0.99 Mb

ARS-BFGL-NGS-5790

26986116

FP, PP

3.26E-14, 9.43E-28

Cole et al., BMC Genomics, 2011 [8]

SAA1

Chr29: 26693328–26696498

24.8 Kb

ARS-BFGL-NGS-24998

26721324

PP

2.96E-08

Cole et al., BMC Genomics, 2011 [8]

  

4.2 Mb

UA-IFASA-8605

30901735

FP, PP

4.90E-13, 1.50E-16

 

ATF3

Chr16: 72820025–72832974

1.9 Mb

ARS-BFGL-NGS-70836

74741746

PP

3.58E-07

Cole et al., BMC Genomics, 2011 [8]

  

3.3 Mb

ARS-BFGL-NGS-85980

76091078

FP, PP

6.46E-07, 8.33E-09

 

RPL23A

Chr11: 21526905–21574655

0.5 Mb

ARS-BFGL-NGS-100459

22128569

PP

1.03E-24

Cole et al., BMC Genomics, 2011 [8]

  

4.0 Mb

BTB-01766447

17484533

FP, PP

4.51E-18, 8.90E-11

 

CDH16

Chr18: 34733117–34743031

0.75 Mb

ARS-BFGL-NGS-107749

33986486

FP, PP

2.54E-13, 3.55E-18

Cole et al., BMC Genomics, 2011 [8]

VEGFA

Chr23: 17255946–17269998

2.9 Mb

ARS-BFGL-NGS-29490

20166517

FP, PP

4.05E-20, 2.32E-26

Cole et al., BMC Genomics, 2011 [8]

  

1.8 Mb

rs29016156

15422973

PP

0.00099

Kolbehdari et al., J Anim Breed Genet, 2009 [5]

  

0.19 Mb

rs41640789

17061460

FP

0.00012

Kolbehdari et al., J Anim Breed Genet, 2009 [5]

BoLA-DQB

Chr23: 25375269–25388620

4.9 Mb

ARS-BFGL-NGS-72191

30279220

FP, PP

8.46E-17, 1.09E-28

Cole et al., BMC Genomics, 2011 [8]

ARID1B

Chr9: 94882343–95271883

0.37 Mb

ARS-BFGL-NGS-81082

94511747

FP, PP

3.00E-11, 2.37E-08

Cole et al., BMC Genomics, 2011 [8]

PTHLH

Chr5: 82246521–82258858

1.5 Mb

Hapmap51303-BTA-74377

83790390

FP

1.20E-06

Jiang et al., Plos One, 2010 [6]

  

0.63 Mb

ARS-BFGL-NGS-29557

81612132

FP, PP

2.97E-13, 5.97E-25

Cole et al., BMC Genomics, 2011 [8]

  

6.2 Mb

rs41590827

76049666

PP

0.00013

Kolbehdari et al., J Anim Breed Genet, 2009 [5]

  

9.9 Mb

rs41569048

92162494

PP

1E-4.72

Schopen et al., J Dairy Sci, 2011 [9]

H4

Chr23: 31665561–31667068

1.4 Mb

ARS-BFGL-NGS-72191

30279220

FP, PP

8.46E-17, 1.09E-28

Cole et al., BMC Genomics, 2011 [8]

FAM71A

Chr16: 72811910–72814133

2.5 Mb

ARS-BFGL-NGS-85980

76091078

FP, PP

6.46E-07, 8.33E-09

Cole et al., BMC Genomics, 2011 [8]

THBS4

Chr10: 10945424–10999244

0.90 Mb

BTB-00411816

11899342

FP, PP

2.71E-14, 3.45E-25

Cole et al., BMC Genomics, 2011 [8]

DDIT3

Chr5: 56285007–56307931

0.46 Mb

ARS-BFGL-NGS-14781

56766165

FP

5.54E-10

Cole et al., BMC Genomics, 2011 [8]

M-SAA3.2

Chr29: 26755567–26759547

34.2 Kb

ARS-BFGL-NGS-24998

26721324

PP

2.96E-08

Cole et al., BMC Genomics, 2011 [8]

  

4.1 Mb

UA-IFASA-8605

30901735

FP, PP

7.90E-13, 1.50E-16

 

HIST1H2AC

Chr23: 31579046–31589230

0.95 Mb

BTA-68781-no-rs

30711619

FP, PP

1.17E-17, 6.08E-27

Cole et al., BMC Genomics, 2011 [8]

P4HA2

Chr7: 23480314–23513315

1.1 Mb

Hapmap49309-BTA-78604

24655689

PP

4.34E-14

Cole et al., BMC Genomics, 2011 [8]

  1. 1,2Means the position on the bovine genome sequence of UMD3.1.66.
  2. PP: protein percentage; FP: fat percentage.