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Figure 3 | BMC Genomics

Figure 3

From: Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity

Figure 3

Platinum-specific phenotype. A) Carboplatin and cisplatin IC50 values vs intrinsic growth rate p <0.0001 r2 = 0.3912 (carboplatin) and p <0.0001 r2 = 0.4854 (cisplatin). B) Carboplatin and cisplatin drug specific phenotypes (DSPs) vs. intrinsic growth rate p = 1.0 r2 = 5.003 × 10-16 (carboplatin) and p = 1.0 r2 = 1.314 × 10-18 (cisplatin). C) Carboplatin and cisplatin IC50 values vs corresponding DSPs p <0.0001 r2 = 0.6088 (carboplatin) and p <0.0001 r2 = 0.5146 (cisplatin).

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