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Table 3 Pathway of RNA-seq involved in immunity and inflammation responses after infection for four weeks

From: De novo assembly and transcriptome characterization: novel insights into the natural resistance mechanisms of Microtus fortis against Schistosoma japonicum

Pathway

DEGs with pathway annotation

All genes with pathway annotation

 

1st w (700)

2nd w (946)

3rd w (665)

4th w (432)

1st w

2nd w

3rd w

4th w

Jak-STAT signaling

15 (2.14%)

22 (2.33%)

13 (1.95%)

5 (1.16%)

577 (1.51%)

577 (1.51%)

577 (1.51%)

577 (1.51%)

MAPK signaling

26 (3.71%)

29 (3.07%)

16 (2.41%)

9 (2.08%)

1058 (2.76%)

1058 (2.76%)

1058 (2.76%)

1058 (2.76%)

apoptosis

9 (1.29%)

12 (1.27%)

5 (0.75%)

3 (0.69%)

373 (0.97%)

373 (0.97%)

373 (0.97%)

373 (0.97%)

NF-kappa B

23 (3.29%)

37 (3.91%)

11 (1.65%)

8 (1.85%)

477 (1.25%)

477 (1.25%)

477 (1.25%)

477 (1.25%)

Toll-like receptor signaling

22 (3.14%)

22 (2.33%)

15 (2.26%)

4 (0.93%)

405 (1.06%)

405 (1.06%)

405 (1.06%)

405 (1.06%)

Natural killer cell mediated cytotoxicity

36 (5.14%)

43 (4.55%)

16 (2.41%)

8 (1.85%)

532 (1.39%)

532 (1.39%)

532 (1.39%)

532 (1.39%)

Fc gamma R-mediated phagocytosis

33 (4.71%)

41 (4.33%)

20 (3.01%)

16 (3.7%)

570 (1.49%)

570 (1.49%)

570 (1.49%)

570 (1.49%)

Complement and coagulation cascades

25 (3.57%)

28 (2.96%)

20 (3.01%)

19 (4.4%)

459 (1.2%)

459 (1.2%)

459 (1.2%)

459 (1.2%)

B cell receptor signaling pathway

22 (3.14%)

35 (3.7%)

15 (2.26%)

11 (2.55%)

424 (1.11%)

424 (1.11%)

424 (1.11%)

424 (1.11%)

T cell receptor signaling pathway

15 (2.14%)

23 (2.43%)

10 (1.5%)

11 (2.55%)

462 (1.21%)

462 (1.21%)

462 (1.21%)

462 (1.21%)

Cytokine-cytokine receptor interaction

21 (3%)

29 (3.07%)

22 (3.31%)

5 (1.16%)

738 (1.93%)

738 (1.93%)

738 (1.93%)

738 (1.93%)

RIG-I-like receptor signaling pathway

8 (1.14%)

10 (1.06%)

6 (0.9%)

2 (0.46%)

245 (0.64%)

245 (0.64%)

245 (0.64%)

245 (0.64%)

NOD-like receptor signaling pathway

8 (1.14%)

9 (0.95%)

6 (0.9%)

2 (0.46%)

343 (0.9%)

343 (0.9%)

343 (0.9%)

343 (0.9%)

TGF-beta signaling pathway

2 (0.29%)

12 (1.27%)

6 (0.9%)

1 (0.23%)

344 (0.9%)

344 (0.9%)

344 (0.9%)

344 (0.9%)

Wnt signaling pathway

5 (0.71%)

12 (1.27%)

3 (0.45%)

3 (0.69%)

630 (1.64%)

630 (1.64%)

630 (1.64%)

630 (1.64%)

Ubiquitin mediated proteolysis

5 (0.71%)

11 (1.16%)

9 (1.35%)

1 (0.23%)

668 (1.74%)

668 (1.74%)

668 (1.74%)

668 (1.74%)

  1. Note: 1st w, first week after infection; 2nd w, second week after infection; 3rd w, third week after infection; 4th w, fourth week after infection.