Table 2 Status of combinations (a) – (d), PAS, SGD and PolC in the non-Firmicutes organisms examined in this study

Trend I

I. polytropus

Fusobacteria

82.8

5.9

1.5

9.8

Y

0.76

***

Y

S. termitidis

89.3

4.1

0.7

5.9

Y

0.73

***

Y

S. moniliformis

92.8

1.8

0.6

4.8

Y

0.84

***

Y

A. laidlawii

Tenericutes

94.6

4.0

0.7

0.7

Y

0.87

***

Y

M. florum

94.9

1.3

2.5

1.3

Y

0.89

***

Y

M. gallisepticum

72.9

8.3

13.5

5.2

Y

0.77

***

Y

U. parvum

66.7

13.3

5.3

14.7

Y

0.6

***

Y

U. urealyticum

66.7

10.3

6.9

16.1

Y

0.67

***

Y

Trend II

S. meliloti

Alphaproteobacteria

35.3

44.9

5.2

14.6

N

0.56

***

N

A. aromaticum

Betaproteobacteria

33.4

51.4

7.9

7.2

N

0.56

***

N

B. thetaiotaomicron

Bacteroidetes/ Chlorobi

30.2

60.5

2.4

6.9

N

0.52

NS

N

P. gingivalis

31.5

38.8

11.6

18.1

N

0.54

*

N

S. ruber

52.0

40.4

5.1

2.5

N

0.57

***

N

C. protochlamydia

Chlamydiae/ Verrucomicrobia

35.3

51.5

6.2

7.1

N

0.51

NS

N

C. trachomatis

35.9

63.1

0.0

1.0

N

0.52

NS

N

T. thermophilus

Deinococcus-Thermus

30.7

53.4

2.7

13.2

N

0.51

NS

N

S. aciditrophicus

Deltaproteobacteria

44.5

38.8

3.2

13.6

N

0.56

***

N

E. minutum

Elusimicrobia

53.7

42.1

0.6

3.7

N

0.65

***

N

C. jejuni

Epsilonproteobacteria

47.0

39.0

3.1

11.0

N

0.6

***

N

H. hepaticus

40.8

48.0

1.7

9.5

N

0.57

***

N

W. succinogenes

31.3

66.7

0.0

2.0

N

0.59

***

N

A. sp.

Gammaproteobacteria

43.2

49.0

4.2

3.6

N

0.59

***

N

E. coli

38.2

49.5

7.1

5.2

N

0.55

**

N

F. tularensis

45.2

43.6

2.7

8.5

N

0.6

***

N

H. ducreyi

35.5

52.1

4.7

7.7

N

0.6

***

N

D. acetiphilus

Other Bacteria

29.8

57.5

3.7

9.0

N

0.56

***

N

L. borgpetersenii

Spirochaetes

33.2

57.6

4.5

4.8

N

0.56

***

N

T. denticola

39.6

40.6

3.2

16.6

N

0.55

***

N

Trend III

W. endosymbiont

Alphaproteobacteria

34.9

12.7

7.9

44.4

N

0.53

NS

N

A. aeolicus

Aquificae

42.6

11.0

9.0

37.4

N

0.52

NS

N

H. Y04AAS1

36.8

13.6

16.1

33.6

N

0.52

NS

N

P. marina

37.3

12.4

7.3

43.0

N

0.52

NS

N

S. YO3AOP1

45.6

3.3

9.9

41.2

N

0.56

***

N

F. nucleatum

Fusobacteria

71.9

2.3

2.3

23.5

N

0.58

***

Y

L. buccalis

68.3

2.9

2.0

26.8

N

0.6

***

Y

M. capricolum

Tenericutes

66.3

8.9

0.0

24.8

N

0.7

***

Y

M. mobile

52.6

9.2

15.8

22.4

N

0.57

**

Y

M. mycoides

59.7

5.0

9.2

26.1

N

0.63

***

Y

M. pulmonis

54.7

13.7

7.4

24.2

N

0.62

***

Y

F. nodosum

Thermotogae

36.6

6.2

17.0

40.2

N

0.53

NS

Y

K. olearia

32.5

3.5

24.6

39.5

N

0.54

*

Y

P. mobilis

44.9

13.9

6.5

34.7

N

0.53

NS

Y

T. africanus

34.3

9.0

24.9

31.8

N

0.56

***

Y

T. maritima

48.7

13.5

7.0

30.8

N

0.5

NS

Y

T. naphthophila

45.0

13.9

6.1

35.0

N

0.52

NS

Y

Trend IV

L. xyli

Actinobacteria

17.4

45.0

13.6

24.0

N

0.61

***

N

M. tuberculosis

22.1

63.6

5.5

8.9

N

0.58

***

N

S. coelicolor

18.6

47.2

19.9

14.3

N

0.55

***

N

A. phagocytophilum

Alphaproteobacteria

14.3

64.0

11.6

10.2

N

0.58

***

N

B. henselae

15.0

82.4

0.0

2.6

N

0.58

***

N

N. sennetsu

4.7

83.5

1.2

10.6

N

0.59

***

N

Z. mobilis

14.9

60.9

12.6

11.6

N

0.56

**

N

C. tepidum

Bacteroidetes/ Chlorobi

14.4

79.1

2.8

3.7

N

0.55

***

N

B. bronchiseptica

Betaproteobacteria

27.1

64.7

4.7

3.6

N

0.55

***

N

N. meningitidis

29.2

55.3

8.9

6.6

N

0.54

**

N

N. europaea

22.9

69.2

3.2

4.7

N

0.51

NS

N

P. necessarius

20.5

77.2

0.0

2.3

N

0.62

***

N

R. solanacearum

28.9

53.4

11.2

6.5

N

0.59

***

N

C. caviae

Chlamydiae/ Verrucomicrobia

15.5

78.5

0.9

5.2

N

0.52

NS

N

W. chondrophila

18.0

78.7

1.0

2.4

N

0.51

NS

N

C. aggregans

Chloroflexi

15.3

62.4

12.0

10.3

N

0.53

*

N

D. CBDB1

15.1

73.4

3.6

7.9

N

0.52

NS

N

M. ruber

Deinococcus- Thermus

26.1

59.3

6.8

7.8

N

0.54

**

N

B. bacteriovorus

Deltaproteobacteria

26.4

72.0

0.5

1.1

N

0.56

***

N

D. psychrophila

9.4

84.7

1.7

4.3

N

0.53

*

N

G. sulfurreducens

22.6

54.2

10.8

12.4

N

0.64

***

N

L. intracellularis

17.2

77.2

0.7

4.8

N

0.5

NS

N

A. vinelandii

Gammaproteobacteria

15.3

66.7

8.2

9.7

N

0.56

***

N

S. amazonensis

19.2

77.8

0.9

2.1

N

0.56

***

N

X. fastidiosa

1.1

81.3

12.0

5.6

N

0.57

***

N

P. limnophilus

Planctomycetes

20.8

48.0

15.2

16.0

N

0.5

NS

N

R. baltica

13.2

57.4

23.0

6.4

N

0.51

NS

N

B. burgdorferi

Spirochaetes

11.0

87.9

1.1

0.0

N

0.66

***

N

S. smaragdinae

16.6

69.7

0.7

13.1

N

0.63

***

N

Trend V

A. capsulatum

Acidobacteria

16.4

38.1

21.3

24.2

N

0.5

NS

N

C. Solibacter

28.0

24.2

21.8

26.0

N

0.53

**

N

B. longum

Actinobacteria

20.5

32.6

38.4

8.5

N

0.54

**

N

N. farcinica

22.3

41.3

21.3

15.1

N

0.57

***

N

C. atlanticus

Bacteroidetes/ Chlorobi

47.8

20.5

2.7

29.0

N

0.51

NS

N

R. RS 1

Chloroflexi

17.9

41.2

26.0

14.8

N

0.51

NS

N

C. sp.

Cyanobacteria

24.3

20.8

28.4

26.5

N

0.51

NS

N

N. sp.

23.8

29.1

25.5

21.6

N

0.5

NS

N

P. marinus

6.0

71.4

0.0

22.6

N

0.52

NS

N

T. erythraeum

32.9

19.5

19.2

28.4

N

0.51

NS

N

D. geothermalis

Deinococcus- Thermus

16.7

48.4

11.8

23.2

N

0.51

NS

N

H. pylori

Epsilonproteobacteria

45.5

23.6

8.5

22.4

N

0.52

NS

N

C. Phytoplasma

Tenericutes

22.7

30.7

28.4

18.2

N

0.56

*

Y

M. synoviae

40.5

20.3

13.9

25.3

N

0.5

NS

Y

O. yellows

12.9

42.4

41.2

3.5

N

0.64

***

Y

T. lettingae

Thermotoga

37.6

30.1

4.2

28.2

N

0.51

NS

Y