Gene | Accession number | Known relation with PrP/nervous system | References |
---|---|---|---|
AKR1C1 | NM_001195574.1 | Putative role in myelin formation | [43] |
HBB | NM_001164428.1 | Putative role in intraneuronal oxygen homeostasis, reduced in Alzheimer's and Parkinson's disease | [44] |
NCAM1 | XM_001083697.2 | PrP/N-CAM complexes found in prion infected N2a cells | [45] |
NR4A2 | NM_001266910.2 | Mutations related to dopaminergic dysfunction, including Parkinson schizophrenia and depression | |
USP16 | NM_001260999.2 | Depletion of USP16 prevented ATMi from restoring transcription after DSB induction | [48] |
CALB1 | XM_001085269.2 | Plays a protective role in neurodegenerative disorders (depleted in HD) | [49] |
DACH1 | XM_001082371.2 | Required for normal brain development | [50] |
LXN | NM_001266988.1 | Marker for the regional specification of the neocortex | [51] |
PIK3R3 | NM_001266826.1 | Linked to β-amyloid plaque formation in AD brain | [52] |
SAP18 | NM_001261034.1 | Possibly related to AD | [53] |
SERPINA3 | NM_001195350.1 | Increased in schizophrenia, SNPs affecting onset and duration of AD | |
TNFSF10 | NM_001266034.1 | Implicated in pathogenesis of MS (causing demyelination) | [56] |
HBA2 | NM_001044724.1 | Putative role in intraneuronal oxygen homeostasis, reduced in Alzheimer's and Parkinson's diseases | [44] |
GNRH1 | NM_001195436.1 | Key regulator of the reproductive neuroendocrine system in vertebrates | [57] |
IRF3 | NM_001135797 | Putative protective role against prion infection | [58] |
APOC1 * | AK240617.1 | Binds to ApoE, risk factor for Alzheimer's disease | [59] |
TM7SF3 | XM_001099269.2 | - | - |
MYBPC1 | XM_001091952.1 | - | - |
TTR | NM_001261679 | Amyloid neuropathies, interaction with Aβ | [60] |