Figure 3
From: An integrated platform for bovine DNA methylome analysis suitable for small samples
Snapshots from the UCSC genomic web-browser describing the genomic locations of two bovine imprinted genes (NNAT and PEG10), positioning of the probes (methylome and transcriptome) and other associated bovine genomic features. MseI recognition sites on genomic DNA result in MseI-MseI fragments. CpG islands may be absent (Area A) or present (Areas B-D). EDMA probes may target CTCF binding sites (blue arrows), which may be proximal (Area A) or within (Area C) the gene body. Other EDMA probes (red arrows) also may overlap with probes the transcriptomic (EMBV3) array or cover CpG islands or non-CpG islands. Probes (red arrows) may also cover intronic or exonic portions of the genome (Area D).