Effects of functional feeds on the lipid composition, transcriptomic responses and pathology in heart of Atlantic salmon (Salmo salar L.) before and after experimental challenge with Piscine Myocarditis Virus (PMCV)

Martinez-Rubio, Laura; Evensen, Øystein; Krasnov, Aleksei; Jørgensen, Sven Martin; Wadsworth, Simon; Ruohonen, Kari; Vecino, Jose LG; Tocher, Douglas R

doi:10.1186/1471-2164-15-462

Table 3 Examples of immune genes that responded to the functional feeds

From: Effects of functional feeds on the lipid composition, transcriptomic responses and pathology in heart of Atlantic salmon (Salmo salar L.) before and after experimental challenge with Piscine Myocarditis Virus (PMCV)

Genbank Or Probename	Gene, Symbol	0 wpc		6 wpc		8 wpc		14 wpc
		CMS1	CMS2	CMS1	CMS2	CMS1	CMS2	CMS1	CMS2
	*Antiviral responses*
BQ035726	Very large inducible GTPase 1-3, vlig	−3.71	−1.87	−1.30	−2.75	−3.53	−4.80	−1.51	−3.71
?	IFN inducible mx protein	−5.37	−2.61	1.23	0.78	−1.77	−4.04	−1.09	−1.08
DY741158	STAT2	−2.70	−4.19	1.26	1.03	1.06	−1.67	1.20	1.08
CB500614	Pyrin, bty	−1.38	−2.76	1.12	−1.03	−2.39	−3.50	−1.79	−1.14
BX909789	IRF4	2.82	2.64	3.28	1.46	−1.73	−2.14	1.31	−1.06
213061919	IRF7	3.33	4.43	−1.01	−1.19	1.54	−1.18	1.27	1.45
DW538275	Receptor-transporting protein 3	−1.90	−2.31	−0.09	−0.43	−0.85	−1.17	0.45	−0.13
	*T cells*
Ssa#TC108524	MHC class I antigen	−2.33	−1.57	−0.36	−1.02	−0.05	−0.34	−0.33	−0.52
?	IFNg	−1.66	−1.09	−2.18	−1.98	−2.44	−1.99	−1.32	−1.91
AY693394	CD8 beta	1.19	−1.35	−2.07	−1.76	−2.02	−1.43	−1.60	−1.74
CA368982	Kidney injury molecule 1, havcr1	1.36	−1.31	−1.46	−1.64	−4.27	−2.62	−1.36	1.19
DY710412	Granzyme A-1, graa	−2.24	1.30	−2.65	−2.18	−3.04	−2.94	−1.04	−2.07
?	Granzyme A-2, graa	−1.48	−1.11	−2.76	−3.27	−3.56	−2.50	−1.19	−2.61
CR369847	NF activated T-cells calcineurin-dependent 1, nfatc1	−1.10	2.27	−1.63	−1.03	4.62	3.09	−1.88	−1.35
	*Inflammatory markers, regulators*
213077403	TNF alpha-induced protein 2, tnfaip2	2.53	2.48	−3.51	−1.35	−2.53	−2.29	2.03	1.11
EG871595	c3a anaphylatoxin chemotactic receptor, c3ar1	−1.02	1.53	1.12	1.13	−2.53	−1.84	−1.17	−1.77
DW576911	Cytochrome P450 family 2 subfamily V, cyp2u1	−1.90	1.13	−5.38	−2.73	−1.74	−2.67	−2.35	−1.54
213081824	FcRgamma-like protein, fcer1g	−6.40	−3.06	−2.44	1.16	−3.18	−2.05	1.20	−2.59
EG881931	TNF decoy receptor, tnfrsf6b	1.36	1.13	−1.73	−1.69	−2.96	−3.18	1.21	−1.10
213081931	Helicase lymphoid-specific, hells	2.24	4.47	1.34	2.20	−2.25	−1.98	−1.06	1.41
CK888744	fetuin B	1.16	1.39	0.87	1.19	1.42	0.58	1.51	−0.56
S48406409	Ly75/CD205	2.79	2.75	−1.13	−1.31	2.06	1.55	−1.27	−1.34

Data are expression ratios (fold changes) of fish fed the functional feeds (CMS1 and CMS2) relative to the REF diet during the course of the infection.

Back to article page

ISSN: 1471-2164

Contact us

Submission enquiries: bmcgenomics@biomedcentral.com
General enquiries: ORSupport@springernature.com

BMC Genomics

Contact us