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Figure 1 | BMC Genomics

Figure 1

From: Identification of tubular injury microRNA biomarkers in urine: comparison of next-generation sequencing and qPCR-based profiling platforms

Figure 1

Gentamicin-induced nephrotoxicity in rats. (A) Urinary protein, β2-microglobulin (B2M), and Kim-1 (all normalized to urine creatinine), indicate tubular injury at D7 (Mean +/- SD; *denotes p value < 0.05). (B) Histopathology assessment of the kidneys revealed moderate degeneration and necrosis with evidence of regeneration of the PCT at day 7. (C) Section of kidney with moderate degeneration and necrosis of the PCT at day 7; Control (0 mg/kg/day), top and 50 mg/kg/day bottom. 10 X, H&E stain. Scale bar = 200 microns.

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