Figure 6

Correlation of ChIP enrichment for individual factors with co-enrichment and predicted affinity. Left to right: (A) Shared enrichment for each factor measured as the Pearson correlation between the TF’s genomewide enrichment landscape (in terms of log₂ fold enrichment) and the median log₂ fold enrichment (MLFE) across all other rich media ChIP-chip experiments. (B) Sequence-specific enrichment for each factor measured as the Pearson correlation between the TF’s genomewide enrichment and the predicted genomewide affinity for that TF from the PBM data of either Badis et al. [28] or Zhu et al. [29] (stronger correlation shown when TF is in both datasets). (C) Scatter plots showing the correlations described above (ChIP enrichment vs. co-enrichment and ChIP enrichment vs. affinity) for each of four factors: Met31p, Reb1p, Abf1p, and Yap1p.