Table 6 Ariadne pathways based on ISACHC3-specific genes differentially regulated in dogs with ISACHC3 heart failure
From: The transcriptomic profile of peripheral blood nuclear cells in dogs with heart failure
Ariadne receptor signaling pathways | The number of genes | p-value |
|---|---|---|
HGFR - > FOXO3A signaling | 3 | 0.00563574 |
ERBB2/3 - > EP300/ETS/ETV/SP1 signaling | 5 | 0.01015 |
EGFR/ERBB2 - > HIF1A signaling | 5 | 0.0128385 |
TNFRSF5/13B - > NFATC1 signaling | 3 | 0.0152928 |
HGFR - > AP-1/CREB/MYC signaling | 5 | 0.0216208 |
AdenosineR - > NF-kB signaling | 4 | 0.0217062 |
ICAM2 - > CTNNB/FOXO/STAT3 signaling | 3 | 0.0242659 |
NeurotensinR - > ELK-SRF/AP-1/EGR signaling | 5 | 0.0248821 |
IL2R - > ELK-SRF/MYC signaling | 4 | 0.0259176 |
InsulinR - > ELK-SRF/SREBF signaling | 4 | 0.0274252 |
GHR - > ELK-SRF/MYC signaling | 4 | 0.0274252 |
KIT - > MITF signaling | 4 | 0.032265 |
IGF1R - > MEF/MYOD/MYOG signaling | 4 | 0.033985 |
UrokinaseR - > ELK-SRF signaling | 4 | 0.0357589 |
IL4R - > ELK-SRF/HMGY signaling | 4 | 0.0375869 |
FibronectinR - > CTNNB signaling | 3 | 0.0381165 |
EDG2 - > ELK-SRF signaling | 4 | 0.0394692 |
EGFR/ERBB3 - > MEF/MYOD/NFATC/MYOG signaling | 6 | 0.0414187 |
FcIgER - > ELK-SRF signaling | 4 | 0.0433973 |
EGFR - > NCOR2 signaling | 4 | 0.0454432 |
GDNF - > HSF1 signaling | 4 | 0.047544 |
ErythropoietinR - > ELK-SRF/FOS signaling | 5 | 0.0477064 |