Figure 3

Chromosome-specific recombination maps. (A) Cumulative frequency graphs representing the observed meiotic COs for each chromosome analyzed (CTO5, CTO6 and CTO9). X-axis represents SC length (in%), position 0 refers to centromeres. Y-axis indicates the frequency of the COs for each position in the SC. The chromosomal regions involved in the rearrangement are depicted as red shadowed areas. Green lines represent the cumulative frequency distribution when two MLH1 foci (COs) are present along the SC, whereas the blue line corresponds to three COs. Red lines depicts the cumulative frequency distribution of all COs detected in CTO6. (B) Schematic representation of chromosomes analyzed, depicting collinear regions in green and inverted regions in purple. BACs used for the chromosome identification are depicted in each case for CTO (left) and HSA (right): RP11-779 N22 and RP11-8 N8 for CTO5, RP11-157 F1 for CTO6 and RP11-926D9 for CTO9.