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Table 6 SNPs with homology to genes of putative immune function mapping near to QTL regions

From: A linkage map of transcribed single nucleotide polymorphisms in rohu (Labeo rohita) and QTL associated with resistance to Aeromonas hydrophila

QTL

Closely mapping SNPs of putative immune function

LG

cM

cM

SNP

GeneID

Length

Hits

E-value

Similarity

1

37.3 and 44.1

32.1

53470_163

Heat shock protein 105kd

615

10

9.33E-87

63.30%

  

32.9

52852_1499

Complement c4

1991

10

0

62.60%

  

37.3

55086_181

Small heat shock protein

857

10

6.64E-44

81.40%

2

43.9, 47.4 and 48.4

48

16321_60

Integrin alpha fg-gap repeat

127

3

5.33E-12

84.33%

3

20.3 and 29

27.4

134389_297

lymphocyte-specific protein tyrosine kinase

435

10

2.66E-64

89.90%

4

0, 0.9, 19.7 and 46.8*

-

-

-

-

-

-

-

5

9.6, 23.8, 38.3 and 43.4

9.6

98520_125

proteasome subunit beta type-6 precursor

168

10

9.08E-20

93.90%

  

13

111876_59

major histocompatibility locus I antigen

250

10

9.21E-33

89.10%

  

18

53025_556

c-type lectin receptor c

1141

10

7.40E-106

62.40%

6

46.9*

46.9

87896_2052

complement protein component c7-1

2667

10

0

71.50%

7

23.4** and 53.7

22.6

110314_603

e3 ubiquitin ligase

888

10

2.19E-138

66.90%

  

54.4

134666_118

immunity related gtpase e4

203

10

2.16E-21

66.70%

8

23.3 and 54.9

54.9

31265_40

CD22 antigen

128

1

1.66E-05

71.00%

9

32.1

-

-

-

-

-

-

-

10

26.1, 29.6 and 34.8

27.9

117051_67

ubiquitination factor e4b isoform 2

116

10

9.21E-12

97.00%

12

31.1 and 37.8

-

-

-

-

-

-

-

13

19.8, 26.9 and 34.9

31

17842_95

mucin 2 protein

172

10

7.15E-17

80.70%

  

31

53178_329

mucin 2 protein

2002

10

0

59.10%

  

31

69593_98

mucin subtype tracheobronchial

307

10

2.79E-45

79.30%

14

1.9*, 12.5*, 24.1*, 43.9* and 47.1**

43.9*

113696_50

perforin 1

233

10

1.23E-24

67.10%

  

47.1

132709_550

chaperonin (HSP60) containing subunit 2

922

10

6.24E-123

95.60%

15

1.1, 12.5*, 26.7, 28.9, 29.1 and 54.4*

26.7

110434_333

t-cell antigen receptor alpha chain c region

381

10

6.69E-31

74.00%

16

23.8 and 39.2

23.8

115737_104

mucin-5b precursor

347

3

9.86E-06

47.00%

18

8.4, 21.5, 35.5*, 48.9 and 49.9*

18.2

133571_269

MHC class II antigen beta chain

391

10

2.05E-32

76.50%

  

36.7

52577_884

heat shock protein 70

2527

10

0

92.60%

19

23.8*

23.8*

111569_63

tributyltin (tbt)-binding protein

393

10

1.91E-46

50.50%

20

0.8, 1.4, 3, 3.3*, 7.9, 9.4, 11.1*, 20.3 and 21.6

-

-

-

-

-

-

-

21

47.1 and 51.1*

45.2

2465_218

ubiquitin-conjugating enzyme e2 c

279

10

1.75E-31

95.30%

22

6, 6.4, 22.3 and 23.2

22.9

83239_350

fish virus induced trim protein

447

10

3.79E-66

65.10%

23

0***, 0.9 and 27.4

0.7

55156_84

dermatin sulphate epimerase

378

10

4.94E-66

80.30%

  

23.2

554_399

dipeptidyl-peptidase 7

502

10

1.19E-67

76.00%

24

49, 51.5 and 55.9*

-

-

-

-

-

-

-

25

46.1

-

-

-

-

-

-

-

  1. GeneID, identity allocated by blast2go using consensus annotations for the top hits. Length, length of query contig sequence. Hits, number of sequences found to match query (maximum 10). E-value, minimum e-value (probability of alignment occurring by chance) recorded for a hit. Similarity, percent mean similarity recorded across hits. *, P <0.05; **, P <0.01; ***, P <0.001 after Bonferroni correction.