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Table 2 Biological pathways significantly ( P < 0.05) associated with antibody mediated immune response of Holstein cattle

From: A genome-wide association study of immune response traits in Canadian Holstein cattle

KEGG1pathway

Count

%

Pvalue

Benjamini2

Systemic lupus erythematosus

19

4.7

2.1E-10

2.2E-08

Type I diabetes mellitus

9

2.2

3.3E-06

1.7E-04

Antigen processing and presentation

11

2.7

4.1E-06

1.4E-04

Olfactory transduction

32

7.9

4.5E-06

1.2E-04

Graft-versus-host disease

8

2.0

5.7E-06

1.2E-04

Allograft rejection

8

2.0

1.4E-05

2.4E-04

Asthma

6

1.5

2.4E-04

3.5 E-03

Autoimmune thyroid disease

7

1.7

5.5 E-04

7.2 E-03

Viral myocarditis

7

1.7

3.5 E-03

4.0 E-02

Intestinal immune network for IgA production

5

1.2

2.7 E-02

2.5 E-02

Spliceosome

8

2.0

2.9 E-02

2.4 E-02

  1. 1Kyoto Encyclopedia of Genes and Genomes.
  2. 2Benjamini = False Discovery Rate α = 0.1.