Table 4 List of Aspergillus nidulans differentially expressed genes (pair-wise comparison of consecutive time points), putatively involved in suberin degradation

Lipid Hydrolysis & Transport

Cutinases

Cutinase 1 (cut 1)

305.8

-3.0

1.5

Extracellular

4^b, 4^c

Cutinase

1.3

-1.2

-1.1

Extracellular

2^b, 2^c

Cutinase (cut2)

-1.3

-1.1

1.1

Extracellular

3^b, 3^c

Cutinase

1.5

-1.4

-1.3

Extracellular

2^b

Other extracellular esterases

Triacylglycerol lipase

22.3

-1.9

1.6

Extracellular

1^b

Lipase/esterase

16.9

-2.0

-3.3

Extracellular

0^b

Putative triacylglycerol lipase

10.4

-1.6

2.7

Extracellular

0^b

Putative triacylglycerol lipase

5.1

13.1

-1.4

Extracellular

1^b

Hydrolase (ester bonds)

3.5

2.2

3.2

Extracellular

0^b

Triacylglycerol lipase

2.9

1.2

1.6

Extracellular

0^b

Hydrolase (ester bonds)

2.3

-1.5

1.0

Extracellular

1^b

Hydrolase (ester bonds)

-2.2

-1.1

-1.1

Extracellular

0^b

Triacylglycerol lipase

-1.5

2.8

1.1

Extracellular

2^b

Triacylglycerol lipase

-6.1

-1.9

1.8

Extracellular

1^b

Carboxylesterase

-7.2

1.3

2.4

Extracellular

1^b

Hydrolase (ester bonds)

-15.9

-1.4

2.3

Extracellular

1^b

Transporters

ABC drug exporter (atrF)

12.0

-1.3

-4.1

Membrane

1^b

ABC transporter

8.6

-2.2

1.2

Membrane

2^b

ABC multidrug transporter (atrD)

5.1

-1.1

-1.7

Membrane

0^b

ABC transporter

4.8

-1.6

-1.2

Membrane

0^b

ABC transporter

4.7

-1.3

-1.9

Membrane

0^b

ABC multidrug transporter

3.6

-3.5

-1.3

Membrane

1^b

ABC multidrug transporter

2.1

-1.3

1.2

Membrane

0^b

Other genes

Long chain fatty alcohol oxidase

1.7

13.7

-1.2

Unknown

2^b

Putative hydrophobic surface binding protein A

9.2

-2.5

1.1

Extracellular

1^b

Fatty Acids β-Oxidation

Transport to the peroxisome/mitochondria

Carnitine acetyltransferase (acuJ)

3.0

-1.6

-1.3

Peroxisome/mitochondria

2^b, 2^c

Carnitine/acyl-carnitine carrier (acuH)

2.0

-2.6

-1.0

Mitochondria

1^b, 1^c

Peroxisomal ATP carrier protein (antA)

4.2

-1.4

-1.2

Peroxisome

3^b, 3^c

β-oxidation cycle

Acetyl-CoA acyltransferase

4.6

-1.7

-1.5

Peroxisome

1^b, 1^c

Acetyl-CoA acyltransferase

-1.2

-2.2

1.3

Mitochondria

0^b

Acyl-CoA dehydrogenase

8.9

-1.1

-1.6

Peroxisome

3^b, 3^c

Acyl-CoA dehydrogenase

2.4

-2.1

1.4

Peroxisome

1^b

Acyl-CoA dehydrogenase

-2.0

-1.1

1.4

Mitochondria

0^b

Acyl-CoA dehydrogenase

-2.8

1.4

1.2

Mitochondria

0^b

Acyl-CoA dehydrogenase

-2.2

-1.5

1.7

Mitochondria

1^b

Acyl-CoA dehydrogenase (acdA)

-2.7

1.6

1.2

Peroxisome

1^b, 1^c

Acyl-CoA dehydrogenase (scdA)

2.1

-1.4

1.1

Mitochondria

3^b, 3^c

Acyl-CoA synthetase (faaB)

7.9

-2.6

-1.4

Peroxisome

2^b, 2^c

Acyl-CoA synthetase (fatA)

3.0

-2.8

1.1

Peroxisome

2^b

Acyl-CoA synthetase (fatD)

1.2

-2.3

-1.6

Peroxisome

1^b

β-ketoacyl-CoA thiolase (mthA)

1.9

-2.2

-1.8

Mitochondria

1^b

Long chain fatty acyl-CoA oxidase (aoxA)

5.7

-1.4

-1.4

Peroxisome

3^b, 3^c

NADP-isocitrate dehydrogenase (idpA)

3.5

-1.5

-1.4

Peroxisome/mitochondria

1^b

Isovaleryl-CoA dehydrogenase (ivdA)

1.1

-1.5

3.0

Mitochondria

0^b

Gluconeogenesis

Transcription activator (acuM)

2.1

-1.6

1.6

Cytosol

2^b

Phosphoenolpyruvate carboxykinase (acuF)

6.8

-3.8

-1.2

Cytosol

1^b

Fructose 1,6-bisphosphatase (acuG)

1.9

-1.8

1.0

Cytosol

2^b

Glyoxylate cycle

Isocitrate lyase (acuD)

2.9

-2.2

-1.7

Peroxisome

1^b,1^c

Malate synthase (acuE)

-1.2

1.2

-1.2

Peroxisome

2^b,2^c

Regulatory genes

Zn₂-Cys₆ transcription factor (farA)

2.8

-1.7

1.3

Nucleus

0^b

Zn₂-Cys₆ transcription factor (farB)

4.2

-1.8

1.0

Nucleus

1^b

Zn₂-Cys₆ transcription factor (scfA)

-2.0

-2.8

-1.1

Nucleus

0^b

Zn₂-Cys₆ transcription factor (facB)

5.4

-2.4

-1.4

Nucleus

0^b