Figure 6From: 8p23 beta-defensin copy number determination by single-locus pseudogene-based paralog ratio tests risk bias due to low-frequency sequence variationsParalogous sequence variation C > T (PSV, chr8: 7277574, rs187261177) in the PRT4 forward primer binding site (5’-CACTTGTCCCACCAACCTTC). Sequencing traces of two clones derived from sample RC081 (CN = 5 by MLPA, CN = 4 by PRT4) represent (A) the major and (B) the minor PSV allele.Back to article page