Figure 5

Enrichment pattern of Pearson correlation coefficients of the co-expressed microRNA-mRNA pairs containing candidate causal MRESS SNPs. We divided pairs with candidate causal MRESS SNPs into ten aliquots according to the correlation coefficients and obtained ten intervals. Then, we counted the number of MRESS SNPs, not necessarily candidate SNPs, falling into each interval. At last, we divided the number of candidate causal MRESS SNPs in each interval by that of the total set and took logarithm. A value greater than zero means microRNA-mRNA pairs containing candidate causal MRESS SNPs enrich in this part, and a value less than zero stands for anti-enrichment. This figure displays significant enrichment at parts of weakly negative correlation and anti-enrichment at parts of positive correlation, which demonstrates pairs containing candidate causal MRESS SNPs are more likely to be interactive.