Figure 2

Identification of β-catenin target genes. DLD1 and SW480 cells were treated with β-catenin siRNA and differentially expressed genes were identified using a DNA microarray. The corresponding data for LS174T cells was published earlier and used for comparison. The Venn-like diagrams display the number of differentially expressed genes when analyzing all differentially expressed genes (A), previously described β-catenin target genes listed in Table 1(B), or 96 genes encoding basic helix-loop-helix (bHLH) proteins (PFAM family PF00010) (C). The names of the genes corresponding to the seven sections of each Venn-like diagram are listed in separate tabs in the Additional files 1, 2 and 3.