From: Genetic and epigenetic regulation of gene expression in fetal and adult human livers
Gene/Locus | Chr | SNP | CpG site | % of variation in expression explained by | |||
---|---|---|---|---|---|---|---|
SNP only | CpG only | SNP and CpG site | SNP and all CpG sites1 | ||||
GSTT1 | 22 | rs9612520 | cg05380919 | 50% | 75% | 78% | 84%** |
CYP3A5 | 7 | CS015290 | cg03133378 | 55% | 7% | 57% | 57% |
GSTM1 | 1 | rs75953876 | cg18938907 | 11% | 55% | 56% | 61% |
GPX7 | 1 | rs11810754 | cg11953272 | 48% | 16% | 49% | 52% |
UGT1A1 | 2 | rs7592624 | cg11811840 | 22% | 41% | 45% | 47% |
SLC22A18 | 11 | rs413781 | cg24724917 | 30% | 15% | 44% | 49%* |
FMO4 | 1 | rs2223477 | cg14981176 | 39% | 16% | 39% | 39% |
GSTM3 | 1 | rs115636764 | cg23645476 | 21% | 20% | 35% | 46%** |
SLC19A1 | 21 | rs7867 | cg27210852 | 22% | 10% | 30% | 30% |
GSTO2 | 10 | rs11595547 | cg23659134 | 20% | 24% | 28% | 28% |
PON1 | 7 | rs854533 | cg07404485 | 13% | 23% | 27% | 30% |
DHRS2 | 14 | rs57350570 | cg07125017 | 23% | 4% | 26% | 26% |
GSTA4 | 6 | rs538920 | cg22486834 | 14% | 14% | 20% | 21% |
CEBPA | 19 | rs80241821 | cg19035908 | 17% | 6% | 20% | 20% |
MGST3 | 1 | rs10737515 | cg16553119 | 12% | 12% | 13% | 13% |
DHRS7 | 14 | rs376391 | cg18906360 | 12% | 9% | 13% | 13% |