Figure 1

Quantified samples in each virus group. (A) Each circle represents an RNA sample isolated from the peripheral blood mononuclear cells (PBMCs) of a cynomolgus macaque. Grey indicates pre-infection samples, each coming from a different cynomolgus macaque. Blue indicates samples infected with Lassa virus, and red indicates samples infected with Marburg virus. All samples were quantified using microarrays. Samples with a black border were also quantified using RNA sequencing. (B) Diagram of the disease timecourse highlighting the most relevant clinical events, from the appearance of fever 3 days post-infection to the late stage of disease and death (see also Table 1).