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Table 1 Cross-validation performance (data set S1676) of our previous work, the single-model method, and the three methods with multiple models.

From: Feature-based multiple models improve classification of mutation-induced stability changes

Method

AUC

MCC

Q2

Se

Sp

PPV

NPV

EASE-AA

0.76

0.35

67.11

74.93

64.22

43.68

87.37

EASE-AA2

0.77

0.38

72.67

65.54

75.31

49.58

85.51

EASE-ASA

0.80

0.40

72.62

71.07

73.19

49.55

87.23

EASE-SS

0.80

0.42

73.57

72.13

74.11

50.79

87.77

EASE-MM

0.82

0.44

74.71

73.14

75.28

52.30

88.33

  1. EASE-MM is a consensus method of EASE-ASA and EASE-SS