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Table 1 Prediction accuracy of HLA-VBSeq and existing tools for HLA typing in the 30x simulation data analysis.

From: HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data

HLA resolution

HLA-VBSeq

PHLAT

HLAminer

8-digit

99.94%

-

-

6-digit

99.95%

80.80%

-

4-digit

99.95%

88.75%

50.12%

2-digit

100%

96.39%

77.82%

  1. The accuracies of each method are calculated at 8-digit, 6-digit, 4-digit, and 2-digit resolution from the 30x simulation data. PHLAT only predicts HLA types at 6-digit, 4-digit and 2-digit resolution, and HLAminer only predicts HLA types at 4-digit and 2-digit resolution.
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BMC Genomics

ISSN: 1471-2164

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