Figure 4

Developmental expression profile of Apba2 . Apba2 expression in the primitive neural tube begins by embryonic day 10 (E10). Expression throughout the neural tube is seen in day E11 and E12, but appears to be restricted to the primitive brain vesicles by day E13 and continues during day E14 in all regions of primitive brain, including medulla, midbrain, thalamus, striatum, olfactory lobe, and neopallial cortex as seen above. By day E15, however, Apba2 transcript also appears in the dorsal root ganglia surrounding the spinal cord.