Table 3 Examples of modules of shared cis-elements found in highly expressed genes in 3 immune tissues. Elements were clustered with at least 2 other cis-elements within a 200 bp window, indicating the presence of a putative regulatory module which contained at least 3 transcription factor binding sites, one of which was required to be a lymphoid element. All are located within 3 kb upstream and 100 bp downstream of the first bp of exon 1. The modules were present in the mouse and human orthologs of at least 2 genes from sets of genes that were highly expressed in thymus, stimulated lymph nodes, or activated T-cells. The number of genes for which orthologs were available: thymus, 7; lymph node, 4; activated T-cells, 17.

From: Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system