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Table 1 Selected GO terms significantly enriched toward high 2 kb upstream alignment scores. P-values are Bonferroni-corrected. b,m,c represents GO hierarchy (b:biological process, m:molecular function, and c:cellular component). mean: mean alignment score. The mean alignment score for all the genes analyzed is 411.01.

From: Genes involved in complex adaptive processes tend to have highly conserved upstream regions in mammalian genomes

GO accession

GO term definition

p-value

mean

# genes

GO:0007275

b

development

2.69E-48

860.98

1432

GO:0009653

b

morphogenesis

2.82E-47

898.06

949

GO:0009887

b

organogenesis

1.50E-42

911.47

765

GO:0048513

b

organ development

1.50E-42

911.47

765

GO:0007154

b

cell communication

8.30E-38

799.48

2473

GO:0007165

b

signal transduction

4.61E-24

791.28

1969

GO:0007399

b

neurogenesis

7.04E-22

945.20

322

GO:0003700

m

transcription factor activity

1.63E-20

892.63

673

GO:0050877

b

neurophysiological process

4.29E-09

836.34

435

GO:0019226

b

transmission of nerve impulse

7.07E-06

888.41

197

GO:0007268

b

synaptic transmission

1.07E-05

889.12

192

GO:0016055

b

Wnt receptor signaling pathway

4.19E-04

989.45

78