From: A gene expression fingerprint of C. elegans embryonic motor neurons
Cosmid Name | Common Name | Rank | KOG (Other description) |
---|---|---|---|
Axon Guidance and Outgrowth | Â | Â | Â |
B0273.4a | unc-5 | 934 | Netrin transmembrane receptor unc-5 |
T19B4.7 | unc-40 | 188 | Receptor mediating netrin-dependent axon guidance |
F41C6.1 | unc-6 | 616 | Netrin, axonal chemotropic factor |
F56D1.4a | clr-1 | 754 | Protein tyrosine phosphatase |
M79.1a | abl-1 | 882 | Protein tyrosine kinase |
F09B9.2 | unc-115 | 696 | Actin-binding LIM Zn-finger protein Limatin involved in axon guidance |
B0350.2 | unc-44 | 449 | Ankyrin |
C01G10.11a | unc-76 | 182 | Kinesin-associated fasciculation and elongation protein involved in axonal transport |
K10D3.2 | unc-14 | 763 | (RUN domain protein required for axonogenesis and sex myoblast migration) |
Wingless Signaling | Â | Â | Â |
K10B4.6 | cwn-1 | 216 | Wnt family of developmental regulators |
Y71F9B.5a | lin-17 | 899 | Smoothened and related G-protein-coupled receptors (Frizzled Receptor) |
Acetylcholine Receptor Subunits | Â | Â | Â |
K11G12.2 | acr-2 | 66 | Acetylcholine receptor |
R01E6.4 | acr-12 | 292 | Acetylcholine receptor |
F21F3.5 | unc-38 | 399 | Acetylcholine receptor |
T05C12.2 | acr-14 | 782 | Acetylcholine receptor |
Y110A7A.3 | unc-63 | 800 | Acetylcholine receptor |
F21A3.7 | Â | 212 | Acetylcholine receptor |
Y105E8A.7 | lev-10 | 323 | Cubilin, multiligand receptor mediating cobalamin absorption |
T14A8.1 | ric-3 | 237 | Unnamed protein (Required for nAChR assembly/trafficking) |
Ligand-gated Ion Channel | Â | Â | Â |
ZC196.7 | glr-5 | 792 | Glutamate-gated kainate-type ion channel receptor subunit GluR5 and related subunits |
T27E9.9 | Â | 41 | Ligand-gated ion channel (glycine/GABA) |
Y71D11A.5 | Â | 502 | Ligand-gated ion channel (glycine/GABA) |
Y46G5A.30 | snf-5 | 686 | Sodium-neurotransmitter symporter |
C09E8.1a | Â | 578 | Sodium-neurotransmitter symporter |
G-proteins | Â | Â | Â |
M01D7.7a | egl-30 | 124 | G protein subunit Galphaq/Galphay, small G protein superfamily |
F08B6.2 | gpc-2 | 469 | G protein gamma subunit |
F56H9.4 | gpa-9 | 638 | G-protein alpha subunit (small G protein superfamily) |
G-protein Pathway Components | Â | Â | Â |
F28C1.2 | egl-10 | 872 | G protein signaling regulators |
C05B5.7 | rgs-1 | 486 | G protein signaling regulators |
F17C8.1 | acy-1 | 884 | Adenylyl cyclase |
R07E4.6 | kin-2 | 467 | cAMP-dependent protein kinase types I and II, regulatory subunit |
C17F4.6 | gcy-19 | 213 | Natriuretic peptide receptor, guanylate cyclase |
C50H2.2 | egl-47 | 432 | (Gαo coupled receptor) |
F57F5.5 | pkc-1 | 747 | Serine/threonine protein kinase |
F39B2.8 | Â | 928 | Predicted membrane protein |
C24A8.4 | Â | 1010 | STE20-like serine/threonine kinase MST |
Neuropeptides | Â | Â | Â |
W07E11.3 | flp-2 | 31 | Unnamed protein (FMRF-like peptide) |
C18D1.3 | flp-4 | 691 | (FMRF-like peptide) |
C03G5.7 | flp-5 | 562 | (FMRF-like peptide) |
F33D4.3 | flp-13 | 15 | Unnamed protein (FMRF-like peptide) |
E03D2.2 | nlp-9 | 234 | Unnamed protein (Neuropeptide-like protein) |
CC4.2 | nlp-15 | 165 | Unnamed protein (Neuropeptide-like protein) |
Y47D3B.2a | nlp-21 | 254 | Unnamed protein (Neuropeptide-like protein) |
F13B12.5 | ins-1 | 200 | (Insulin-like peptide) |
T28B8.2 | ins-18 | 767 | Unnamed protein (Insulin-like peptide) |
F56A11.5 | Â | 928 | Uncharacterized Fe-S protein |
Neuropeptide Processing and Secretion | Â | Â | Â |
T03D8.3 | Â | 613 | Proprotein convertase (PC) 2 chaperone involved in secretion (neuroendocrine protein 7B2) |
C32E8.7 | ric-19 | 20 | Secretory vesicle-associated protein ICA69, contains Arfaptin domain |
ZK897.1 | unc-31 | 588 | Ca2+-dependent activator protein |
Neuropeptide Receptor | Â | Â | Â |
T05A1.1 | npr-2 | 362 | 7 transmembrane receptor (neuropeptide receptor family) |
F59D12.1 | Â | 797 | 7 transmembrane receptor (rhodopsin-like GPCR) |
T07D4.1 | Â | 77 | 7 transmembrane receptor (rhodopsin-like GPCR) |
Y62E10A.4 | Â | 275 | 7-transmembrane receptor (rhodopsin-like GPCR) |
K07E8.5 | Â | 452 | Unnamed protein (FMRF receptor) |
C35A11.1 | Â | 814 | Unnamed protein (rhodopsin-like GPCR) |
ZC84.4 | Â | 708 | 7 transmembrane receptor (rhodopsin-like GPCR) |
F56B6.5 | uvt-6 | 629 | 7 transmembrane receptor (somatostatin receptor) |
F56A11.5 | Â | 928 | Uncharacterized Fe-S protein (Neuropeptide receptor activity) |