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Table 2 Direct interactions between LET-756 (DB) and clones derived from the ORFeome library. A) clones detected in the screening of the C. elegans libraries; B) orthologs of clones detected in the screening of the human placenta library; C) orthologs of known mammalian FGF interactors.

From: Direct and heterologous approaches to identify the LET-756/FGF interactome

 

Interactors (AD)

LET-756 (DB)

  

LacZ

3-AT

URA

A

RPS-16

+/-

++

-

 

PAL-1

++

+

-

 

DAF-21

-

+*

-

 

COL-129

+/-

+

-

 

SKR-2

+/-

+/-

-

 

C15C6.2

+/-

+

-

B

KIN-10 (CSNK2B, CK2β)

+/-

+

-

 

KIN-3 (CSNK2A, CK2α)

-

+

-

 

HSP-6 (HSPA9B, mortalin)

-

+

-

 

F14E5.2 (GLG1, CFR)

-

+/-

-

 

C18A3.3 (EBNA1BP2, NoBP)

-

+/-

-

 

RPL-6 (RPL6)

+/-

+

-

C

FTT-1/PAR-5 (YWHAB, 14-3-3β)

+/-

+

-

 

FTT-2 (YWHAB, 14-3-3β)

+/-

+

-

 

ZYX-1a, ZYX-1b (ZN420)

-

-

-

  1. *: 3-AT concentration allowing yeast growth was 20mM except for DAF-21 where it was 40 mM